Gastroesophageal reflux disease (GERD) can be treated using a vonoprazan-first strategy (first-line treatment with vonoprazan), or esomeprazole-first/rabeprazole-first strategies (first-line treatment with proton-pump inhibitors [PPIs], esomeprazole/rabeprazole, followed by a switch to vonoprazan). This cost-utility analysis used long-term simulation modeling to evaluate the cost-effectiveness of a vonoprazan-first strategy compared with the esomeprazole-first and rabeprazole-first strategies. If your baby has symptoms of GERD, the first thing you should do is talk to your child’s doctor. They can suggest ways to change your child’s sleeping and eating habits that might help.
This study suggests that the risk of a hip fracture that is specifically related to PPI use is about 2 per 1,000 patient-years. A recent report in the Journal of the American Medical Association (JAMA) looked at the medical records of over 9 million people in the United Kingdom. They were able to identify over 13,000 people with a hip fracture and compare them to over 135,000 people who did not have a hip fracture.
Background The District Health Information System 2 (DHIS2) is a tool for collection, validation, analysis and presentation of both individual (tracker) and aggregated data tailored to integrated health information management activities. DHIS2, developed by the Health Information Systems Programme (HISP) in collaboration with University of Oslo, is a modular web-based software package built with open source Java frameworks.
The study was done to ascertain the prevalence rate of HIV, HIV-HBV and HBV co-infections amongst health care workers in Ibadan, Nigeria. Background HIV/AIDS represents one of the major health challenges of Ethiopia, despite a proven record of universal access to HIV treatment and care. Long-term antiretroviral therapy (ART) retention is a key factor for personal and public health benefits. Identification of determinants of attrition is needed to design appropriate interventions.
However, South African men also had a higher risk of KS than European men after adjustment for HIV-related factors. Besides differences in HHV-8 prevalence, other factors such as environmental exposures and malaria may play a role [28-30].
Coprological assessment for parasites was based on the Kato-Katz technique in both dry and rainy seasons at baseline, 21 days and 3 months post treatment. Single dose albendazole treatment was administered to all patients at baseline. Conclusions Half of the young children included in this study had detectable HBV DNA and showed lamivudine resistance. Uncontrolled HBV infection is associated with an increased risk of severe liver damage and hepatocellular carcinoma. HBsAg screening of HIV-infected children, using cost-effective point-of-care methods, and treatment with tenofovir should be made more widely available in resource-limited settings.
Information on side effects from studies where a PPI is compared to a placebo show that the most common side effects are headache, abdominal pain, bloating, diarrhea and nausea. They occur in 1-2% of patients given PPIs. Proton pump inhibitors (PPIs) are the most commonly prescribed class of medication for the treatment of heartburn and acid-related disorders. They work by blocking the site of acid production in the parietal cell of the stomach. The bottom lineIt’s important for patients to pay attention to the frequency and severity of their symptoms, and to see a doctor if they suspect they might have GERD, because GERD can cause severe complications if left untreated.
Methods We used data from the CASA project, a prospective, multisite study of a cohort of HIV-infected patients who started ART in seven urban and rural health facilities located in the Tigray. We analysed the retention in care and its associated determinants in over 1000 patients followed for two years. The main outcome measure was the retention in care rate, defined as the proportion of patients receiving and alive ART at the same health facility as at ART initiation. Kaplan-Meier method was used to estimate the probability of retention at different time points. Cox Proportional Hazards model with robust sandwich estimates to account for within health facility correlation was used to identify factors associated with retention.
Prescription medications can provide stronger relief from GERD symptoms. Certain prescription-strength medications, such as prescription PPIs, can help heal damage to the esophagus caused by acid reflux also. Results The decision to conduct a PrEP study was based on the outcome of a modelling study that suggested that sero-discordant couples will benefit from access to condom, TasP, and PrEP. Next, the decisions on the target population for the PrEP demonstration study, the models for evaluation at specific project site, and the design of the community engagement programme were reached through a formative research which engaged 611 individuals using multiple media. The study did not exclude study participants based on Hepatitis status and HIV risk profile since Truvada was an effective hepatitis treatment and the prevalence of hepatitis infection is high in Nigeria.
P. S. Ly (TAHOD Steering Committee member [TSC]) and V. Khol, National Center for HIV/AIDS, STDs and Dermatology, Phnom Penh, Cambodia; F. J. Zhang (TSC and TAHOD Steering Committee cochair), H. X. N and Zhao. Han, Beijing Ditan Hospital, Capital Medical University, Beijing, China; M. P. Lee (TSC), P.
During each survey, after a brief physical examination, blood was taken from each volunteer by finger prick to perform thin and thick blood film examination. Blood smears collected were air dry and the thin film fixed with methanol. Dry smears were then stained with controlled PH Giemsa buffer solution and checked for malaria parasite using light microscope. Background Children born to mothers who had malaria in pregnancy have an increased risk of malaria infection in the first 24 months of life and they also experience earlier episodes of malaria compared to their counterparts. This study compared the pre- and post-seasonal prevalence of P. falciparum infection and anti-malarial antibodies among children whose mothers received either intermittent preventive treatment in pregnancy using sulphadoxine-pyrimethamine (IPTp-SP) plus community-based scheduled screening and treatment (CSST) of malaria in pregnancy or standard IPTp-SP.
Antacids. Popular over-the-counter medications like Tums, Maalox, Mylanta and Rolaids neutralize stomach acid and provide fast-acting relief in mild or isolated cases of acid reflux.
Methods This was a twelve months longitudinal study. A total of 412 subjects including school children (between the ages of 2-17 years) and pregnant women were randomly selected from four endemic communities in Kpandai district of the Northern region.
All rights reserved. Participants ages 70-89 years were randomized to a physical activity (PA) or successful aging (SA) intervention and evaluated by medication use. Confounders included baseline demographic characteristics, physical function, cognitive function, sleep quality, and acid reflux symptoms, which were adjusted via propensity score weighting. Outcomes were incident and persistent major mobility disability (MMD and pMMD) and injurious falls. Weighted proportional hazard models evaluated independent and interaction effects of PPIs and H2RAs.
Uy, and R, Bantique, Research Institute for Tropical Medicine, Manila, Philippines; W. W. Wong (TSC and TAHOD Steering Committee chair), W. W. Ku, and P. C. Wu, Taipei Veterans General Hospital, Taipei, Taiwan; O. T. Ng (TSC), P.