You might need to take one of the many excellent medicines for osteoporosis. Formal studies looking at the use of PPIs in hundreds of patients showed virtually no long term side effects. As a result, new PPIs were developed, PPIs became generic and ultimately available over the counter without a prescription.
1. Consumers Union. Proton pump inhibitors (PPI) medicines review. Consumer Reports Best Buy Drugs.
AcipHex has been a life saver for me! Last year I started treatment for Lupus, which included a great deal of medications, all of which made my already present heartburn a million times worse! It was so terrible I actually had to have an endoscopy to ensure there was nothing wrong with my stomach. I tried several types of heartburn medication.
Proton pump inhibitors such as rabeprazole stop cells in the lining of the stomach from producing too much acid. This helps to prevent ulcers from forming, or assists the healing process where damage has already occurred. By decreasing the amount of acid, they can help to reduce the symptoms of acid reflux disease also, such as heartburn.
Recent studies suggest that there may be a slight increase in the risk of bone fractures when proton pump inhibitors like rabeprazole are taken for longer than a year. If this affects you, your doctor will check that you are taking enough vitamin calcium and D to reduce this risk. Smoking increases the amount of acid produced by the stomach and may make your symptoms worse. If you are a smoker, speak with your doctor or pharmacist about how to quit. If you are overweight, it puts extra pressure on your stomach and encourages the symptoms of acid reflux.
Use of Aciphex for IBS For a number of years now I have been taking Aciphex for GERD (gastroesophageal reflux disease) and have not noiced that it has helped with any of the symptoms of IBS. Causes vertebral fractures and bone problems with prolonged use, per study that I read about, printed in CNN.com. Do the extensive research. Recommendation is to take it for 14 days in a row now, and no more. It does such a effective job Apparently, that, with the lack of acid in the stomach, the calcium and minerals do not get broken-down to be delivered to the bones.
There have been other reports over the past couple of years about the possible risk of pneumonia and infections of the colon with a bacterium called clostridium difficile in patients taking PPIs. Again, these articles looked at the medical records of hundreds of thousands of patients and found a small increased risk in patients using PPIs. Additionally, like the hip fracture study, other medical illness such as diabetes, heart and lung disease were also important risk factors. Information on side
The article reviews evidence that patients 50 years old or older who take proton pump inhibitors (PPIs — a list of the six approved ones is in the article) or use them for a year or more may be at increased risk of fractures of the hip, wrist and spine. Since much of the use of these drugs is inappropriate and unnecessarily dangerous, the article discusses pharmacologic and non-pharmacologic alternatives to PPIs.
Others have switched to prescription brands like Prevacid, Nexium, Aciphex and Protonix, which cost five to six times as much. Eisai derives nearly half of its U.S. drug sales from Aciphex and it is its second-biggest selling drug after Aricept, which is used to treat Alzheimerâ€™s disease. After finishing the long Prilosec treatment, I wanted to try a natural, safe supplement of staying on Prilosec to help with my acid reflux instead.
This was a great advance in our ability to treat the millions of patients worldwide that have acid-peptic diseases. In the 1980â€™s there were concerns that, by profoundly decreasing stomach acid production, they might lead to other health problems such as serious infections, poor absorption of vitamins and minerals, even gastrointestinal cancers.
Studies like this talk about the risk per patient-year of follow up. For example if one follows 100 patients for 10 years, that is 1,000 patient-years of follow-up. This study suggests that the risk of a hip fracture that is specifically related to PPI use is about 2 per 1,000 patient-years. In the last few years, researchers have been able to evaluate the side effects and complications of medications by using large databases of millions of patients. Interestingly, the incidence of these side effects is the same as when patients take the placebo.